(For adults only): Take on an empty stomach during the day: For mood balance: 1-4 tables 2 times per day or as directed by a health professional. For joint support: 1-3 tablets 2 times per day or as directed by a health professional. Do not exceed a total of 8 tablets per day. For best results, take SAMe for a minimum of 2 weeks, at which time effects should be observed.

For optimum freshness, refrigerate after opening.

As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery. Individuals with bipolar disorder or depression, anxiety disorders, or taking antidepressant medication should consult with their health professional prior to use. Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.